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ORFcurator

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ORFcurator

About ORFcurator

About the Database Sequences

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In recent years, genomic sequence data have become available at a staggering rate. The unassembled, and often incomplete, genome sequences are generally stored as draft sequences across multiple institutions. These unpublished sequences may contain information that may be useful to researchers before they are fully annotated and published. The development of curation tools that are able to mine and provide sequence data in formats that can be used in subsequent phylogenetic analyses is essential. Furthermore, the identification of similar, evolutionarily conserved genes and gene clusters across prokaryotic genomes may offer valuable insight to evolutionarily maintained biochemical processes. To facilitate the accurate and rapid identification of conserved gene clusters, we developed this application, called ORFcurator. This application automates the process of discovering putative genes from publicly available genome sequence databases. Additionally, it identifies gene clusters across a range of organisms stored in a locally curated database. All data output are in a form that can be easily imported into many popular phylogenetic analysis software applications.

Sample Sequences used to test ORFcurator
Widespread Colonization Island (WCI):
    Actinobacillus actinomycetemcomitans CU1000   GenBank   seqs
  Caulobacter crescentus CB15   GenBank   seqs

'seqs' are ready to copy and paste into ORFcurator